Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann–Pick disease type C1 | Scientific Reports
JCM | Free Full-Text | Molecular Genetics of Niemann–Pick Type C Disease in Italy: An Update on 105 Patients and Description of 18 NPC1 Novel Variants
Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteins | SpringerLink
NPC1, intracellular cholesterol trafficking and atherosclerosis. | Semantic Scholar
MARCH6 may contain a sterol sensing domain (A) % similarity of SSDs... | Download Scientific Diagram
Cholesterol transport in the lysosome. Upon being delivered to the... | Download Scientific Diagram
Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | eLife
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications
NPC1 structure and proposed pathway of cholesterol binding (A)... | Download Scientific Diagram
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2 - ScienceDirect
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram
Schematic representation of the NPC1 protein (not to scale). Cylinders... | Download Scientific Diagram
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications
JCM | Free Full-Text | Molecular Genetics of Niemann–Pick Type C Disease in Italy: An Update on 105 Patients and Description of 18 NPC1 Novel Variants
Figures and data in Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins | eLife
Human NPC1: topology, structure, and function. (A) Predicted topology... | Download Scientific Diagram
Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | eLife
Role of the SSD within NPC1 in mediating the binding between NPC1... | Download Scientific Diagram
Guilty until proven innocent: the case of NPC1 and cholesterol: Trends in Biochemical Sciences
IJMS | Free Full-Text | Cholesterol Transport in Wild-Type NPC1 and P691S: Molecular Dynamics Simulations Reveal Changes in Dynamical Behavior
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C - ScienceDirect
